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>   home   >   Products   >   Primary Antibodies   >   Mbd3 antibody - N-terminal region   

Mbd3 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Mbd3 antibody - N-terminal region AI11692

    WB Suggested Anti-Mbd3 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Mouse Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Z2D8
Other Accession NM_013595, NP_038623
Reactivity Human, Mouse, Rat, Dog
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 32kDa
Additional Information
Gene ID 17192
Alias Symbol AI181826, AU019209
Other Names Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, Mbd3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Mbd3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMbd3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mbd3
Function Acts as transcriptional repressor and plays a role in gene silencing. Does not bind DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (By similarity). Recruits histone deacetylases and DNA methyltransferases.
Cellular Location Nucleus. Chromosome Note=Detected on chromatin, at promoter regions of active genes (By similarity). Nuclear, in discrete foci.
Tissue Location Highly expressed in brain, heart, kidney, liver, lung, skeletal muscle, spleen and testis. Detected at lower levels in embryonic stem cells.
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$ 293.00
Cat# AI11692
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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