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Prmt7 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Prmt7 antibody - C-terminal region AI11697

    WB Suggested Anti-Prmt7 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Thymus
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q922X9
Other Accession NM_145404, NP_663379
Reactivity Human, Mouse, Rat, Horse, Dog
Predicted Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 78kDa
Additional Information
Gene ID 214572
Alias Symbol 4933402B05Rik, BC006705, MGC7929
Other Names Protein arginine N-methyltransferase 7, 2.1.1.-, Histone-arginine N-methyltransferase PRMT7, 2.1.1.125, [Myelin basic protein]-arginine N-methyltransferase PRMT7, 2.1.1.126, Prmt7, Kiaa1933
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Prmt7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPrmt7 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Prmt7
Synonyms Kiaa1933
Function Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo (By similarity).
Cellular Location Cytoplasm, cytosol. Nucleus
Citations (0)
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$ 389.00
Cat# AI11697
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