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PRMT1 antibody - middle region

Rabbit Polyclonal Antibody

  • IHC - PRMT1 antibody - middle region AI11699
    Rabbit Anti-PRMT1 Antibody
    Paraffin Embedded Tissue: Human Kidney
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
  • WB - PRMT1 antibody - middle region AI11699

    WB Suggested Anti-PRMT1 Antibody Titration: 5.0μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99873
Other Accession NM_001536, NP_001527
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rabbit, Zebrafish, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 3276
Alias Symbol ANM1, HCP1, IR1B4, HRMT1L2
Other Names Protein arginine N-methyltransferase 1, 2.1.1.-, Histone-arginine N-methyltransferase PRMT1,, Interferon receptor 1-bound protein 4, PRMT1, HMT2, HRMT1L2, IR1B4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-PRMT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPRMT1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRMT1
Synonyms HMT2, HRMT1L2, IR1B4
Function Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Methylates FOXO1 and retains it in the nucleus increasing its transcriptional activity.
Cellular Location Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Note=Mostly found in the cytoplasm. Colocalizes with CHTOP within the nucleus. Low levels detected also in the chromatin fraction (By similarity).
Tissue Location Widely expressed.
Research Areas
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Adams,M.M., (2005) Cell Cycle 4 (12), 1854-1861Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 232.00
Cat# AI11699
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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