|Other Accession||NM_006479, NP_006470|
|Reactivity||Human, Rat, Rabbit, Pig, Horse, Yeast, Dog|
|Predicted||Human, Rabbit, Pig, Horse, Dog|
|Other Names||RAD51-associated protein 1, RAD51-interacting protein, R51A1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RAD51AP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RAD51AP1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.|
|Cellular Location||Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci.|
|Tissue Location||Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Obama,K., (2008) Clin. Cancer Res. 14 (5), 1333-1339 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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