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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KHDRBS1 antibody - N-terminal region   

KHDRBS1 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - KHDRBS1 antibody - N-terminal region AI11782

    WB Suggested Anti-KHDRBS1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human heart
  • IHC - KHDRBS1 antibody - N-terminal region AI11782
    Rabbit Anti-KHDRBS1 antibody
    Paraffin Embedded Tissue: Human Heart cell
    Cellular Data: cardiac cell of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07666
Other Accession NM_006559, NP_006550
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Predicted Human, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 10657
Alias Symbol FLJ34027, Sam68, p62, p68
Other Names KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, KHDRBS1 (HGNC:18116)
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-KHDRBS1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKHDRBS1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KHDRBS1 (HGNC:18116)
Function Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species according to (PubMed:22253824).
Cellular Location Nucleus. Membrane
Tissue Location Ubiquitously expressed in all tissue examined. Isoform 1 is expressed at lower levels in brain, skeletal muscle, and liver whereas isoform 3 is intensified in skeletal muscle and in liver.
Research Areas
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Duran,A., (2008) Cancer Cell 13 (4), 343-354 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11782
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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