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Fnbp1 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Fnbp1 antibody - N-terminal region AI11798

    WB Suggested Anti-Fnbp1 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q80TY0
Other Accession NM_001177650, NP_001171121
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 14269
Alias Symbol 1110057E06Rik, 2210010H06Rik, FBP1, Fbp17
Other Names Formin-binding protein 1, Formin-binding protein 17, Fnbp1, Fbp17, Kiaa0554
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Fnbp1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFnbp1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fnbp1
Synonyms Fbp17, Kiaa0554
Function Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May act as a link between RND2 signaling and regulation of the actin cytoskeleton. May be required for the lysosomal retention of FASLG/FASL (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex Lysosome. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Enriched in cortical regions coincident with F-actin. Also localizes to endocytic vesicles and lysosomes
Tissue Location Expressed in brain and testis.
Research Areas
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$ 293.00
Cat# AI11798
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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