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PTBP2 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - PTBP2 antibody - N-terminal region AI11831

    WB Suggested Anti-PTBP2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: PANC1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKA9
Other Accession NM_021190, NP_067013
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 58155
Alias Symbol FLJ34897, MIBP, PTB, PTBLP, brPTB, nPTB, nPTB5, nPTB6, nPTB7, nPTB8
Other Names Polypyrimidine tract-binding protein 2, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB-like protein, PTBP2, NPTB, PTB, PTBLP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PTBP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPTBP2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTBP2
Function RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Cellular Location Nucleus.
Tissue Location Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues Isoform 3 and isoform 4 are expressed in non-neuronal tissues Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues.
Research Areas
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Galban,S., (2008) Mol. Cell. Biol. 28 (1), 93-107 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11831
(40 western blots)
Availability: 2-3 days
Bulk Size
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