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Rbm25 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Rbm25 antibody - middle region AI11832

    WB Suggested Anti-Rbm25 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession B2RY56
Other Accession NM_027349, NP_081625
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Yeast, Bovine, Dog
Predicted Human, Mouse, Rabbit, Zebrafish, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 99kDa
Additional Information
Gene ID 67039
Alias Symbol 2600011C06Rik, 2610015J01Rik, A130095G20Rik, AI159652, AL023075, AU043498, RNPC7
Other Names RNA-binding protein 25, RNA-binding motif protein 25, Rbm25
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rbm25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRbm25 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rbm25
Function RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA (By similarity).
Cellular Location Nucleus speckle {ECO:0000255|PROSITE- ProRule:PRU00627}. Cytoplasm. Note=Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint (By similarity)
Research Areas
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$ 293.00
Cat# AI11832
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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