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MGC27016 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q8TBY0 |
| Other Accession | NM_144979, NP_659416 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Rat, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59kDa |
| Gene ID | 166863 |
|---|---|
| Alias Symbol | CT68, MGC27016 |
| Other Names | Probable RNA-binding protein 46, Cancer/testis antigen 68, CT68, RNA-binding motif protein 46, RBM46 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-MGC27016 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | MGC27016 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBM46 |
|---|---|
| Function | Essential for male and female fertility, playing a crucial role in regulating germ cell development by ensuring the proper progression of meiosis prophase I (By similarity). Regulates mitotic- to-meiotic transition in spermatogenesis by forming a complex with MEIOC and YTHDC2 which recognizes and down-regulates mitotic transcripts for a successful meiotic entry (By similarity). Required for normal synaptonemal complex formation during meiosis, binding meiotic cohesin subunit mRNAs containing GCCUAU/GUUCGA motifs in their 3'UTRs regions and positively regulating their translation (By similarity). Required for spermatogonial differentiation in both developing and adult testis (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P86049}. |
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Provided below are standard protocols that you may find useful for product applications.
References
Strausberg,R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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