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Fmo1 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Fmo1 antibody - N-terminal region AI11900

    WB Suggested Anti-Fmo1 Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Muscle
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P36365
Other Accession NM_012792, NP_036924
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 60kDa
Additional Information
Gene ID 25256
Alias Symbol RFMO1A
Other Names Dimethylaniline monooxygenase [N-oxide-forming] 1, 1.14.13.8, Dimethylaniline oxidase 1, Hepatic flavin-containing monooxygenase 1, FMO 1, Fmo1, Fmo-1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Fmo1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFmo1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fmo1 {ECO:0000312|RGD:2622}
Function Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PubMed:8504165). Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (By similarity). In vitro, catalyzes the N- oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L- carnitine (PubMed:8504165).
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Expressed in liver, lung and kidney and to a lesser extent in the heart and brain.
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$ 389.00
Cat# AI11900
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