|Other Accession||NM_020477, NP_065210|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Dog|
|Predicted||Human, Mouse, Rat, Rabbit|
|Alias Symbol||ANK, SPH1, SPH2|
|Other Names||Ankyrin-1, ANK-1, Ankyrin-R, Erythrocyte ankyrin, ANK1, ANK|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ANK1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ANK1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions.|
|Cellular Location||Isoform Er1: Cytoplasm, cytoskeleton. Note=Probably the other erythrocyte (Er) isoforms, are located near the surface of erythrocytic plasma membrane Isoform Mu18: Sarcoplasmic reticulum Isoform Mu20: Sarcoplasmic reticulum|
|Tissue Location||Isoform Mu17, isoform Mu18, isoform Mu19 and isoform Mu20 are expressed in skeletal muscle. Isoform Br21 is expressed in brain.|
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