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RHAG antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q02094 |
| Other Accession | NM_000324, NP_000315 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Dog |
| Predicted | Human, Rat, Chicken, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Gene ID | 6005 |
|---|---|
| Alias Symbol | RH2, RH50A, Rh50, Rh50 GP, CD241, Rh50GP, SLC42A1 |
| Other Names | Ammonium transporter Rh type A, Erythrocyte membrane glycoprotein Rh50, Erythrocyte plasma membrane 50 kDa glycoprotein, Rh50A, Rhesus blood group family type A glycoprotein, Rh family type A glycoprotein, Rh type A glycoprotein, Rhesus blood group-associated ammonia channel, Rhesus blood group-associated glycoprotein, CD241, RHAG, RH50 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-RHAG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RHAG antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHAG (HGNC:10006) |
|---|---|
| Synonyms | RH50 |
| Function | Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane (PubMed:11861637, PubMed:11062476, PubMed:15856280, PubMed:19273840, PubMed:21849667, PubMed:22012326, PubMed:24077989, PubMed:15572441, PubMed:26354748). The transport of NH4(+) is electrogenic and masks the NH3 transport (PubMed:26354748). Also, may act as a CO2 channel (PubMed:19273840, PubMed:17712059, PubMed:24077989). In vitro, leaks monovalent cations (PubMed:18931342, PubMed:21849667). Moreover in erythrocyte, regulates RHD membrane expression (PubMed:12130520) and is associated with rhesus blood group antigen expression (PubMed:19744193, PubMed:12130520). |
| Cellular Location | Membrane; Multi-pass membrane protein Note=Localization at the plasma membrane is regulated by ANK1 |
| Tissue Location | Erythrocytes. |
Research Areas
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 339.00
Cat# AI11929
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