UROD antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P06132 |
Other Accession | NM_000374, NP_000365 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Sheep, Horse, Yeast, Bovine, Dog |
Predicted | Human, Zebrafish, Pig, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40kDa |
Gene ID | 7389 |
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Alias Symbol | PCT, UPD |
Other Names | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-UROD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | UROD antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UROD (HGNC:12591) |
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Function | Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352, PubMed:18004775). Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:12071824). |
Cellular Location | Cytoplasm. |
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