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UROD antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - UROD antibody - N-terminal region AI11933
    Rabbit Anti-UROD Antibody
    Paraffin Embedded Tissue: Human Kidney
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
    detail
  • WB - UROD antibody - N-terminal region AI11933

    WB Suggested Anti-UROD Antibody Titration: 2.5μg/ml
    Positive Control: HepG2 cell lysate
    UROD is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P06132
Other Accession NM_000374, NP_000365
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Sheep, Horse, Yeast, Bovine, Dog
Predicted Human, Zebrafish, Pig, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 7389
Alias Symbol PCT, UPD
Other Names Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-UROD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUROD antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UROD (HGNC:12591)
Function Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352, PubMed:18004775). Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:12071824).
Cellular Location Cytoplasm.
Research Areas
Citations (0)
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$ 339.00
Cat# AI11933
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