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CYB561 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P49447 |
| Other Accession | NM_001915, NP_001906 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Dog |
| Predicted | Mouse, Rat, Rabbit, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27kDa |
| Gene ID | 1534 |
|---|---|
| Alias Symbol | FRRS2 |
| Other Names | Cytochrome b561, Cytochrome b-561, CYB561 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CYB561 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CYB561 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CYB561 (HGNC:2571) |
|---|---|
| Function | Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000250|UniProtKB:P10897}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}. Note=Secretory vesicle containing catecholamines and amidated peptides {ECO:0000250|UniProtKB:P10897} |
| Tissue Location | Expressed in many tissues, in particular the brain especially in the cortex and hippocampus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Fung,M.M., (2008) Circulation 117 (4), 517-525 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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