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HP antibody - N-terminal region

Rabbit Polyclonal Antibody

  • IHC - HP antibody - N-terminal region AI11988
    HP (haptoglobin)antibody - N-terminal region (AI11988)
    Catalog Number: AI11988
    Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm in hepatocytes
    Primary Antibody
    Concentration: 1:100
    Secondary Antibody: Donkey anti-Rabbit-Cy3
    Secondary Antibody
    Concentration: 1:200
    Magnification: 20X
    Exposure Time: 0.5 - 2.0 sec
  • WB - HP antibody - N-terminal region AI11988

    WB Suggested Anti-HP Antibody Titration: 0.2-1 μg/ml
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00738
Other Accession NM_005143, NP_005134
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Additional Information
Gene ID 3240
Alias Symbol hp2-alpha, BP, HPA1S, HP2ALPHA2
Other Names Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain, HP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HP
Function As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
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Borsody,M., (2006) Neurology 66 (5), 634-640Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11988
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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