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SLC20A2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q08357 |
| Other Accession | NM_006749, NP_006740 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog |
| Predicted | Mouse, Rabbit, Chicken, Horse, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 70kDa |
| Gene ID | 6575 |
|---|---|
| Alias Symbol | GLVR2, Glvr-2, MLVAR, PIT-2, Ram1, pit2, hPit2 |
| Other Names | Sodium-dependent phosphate transporter 2, Gibbon ape leukemia virus receptor 2, GLVR-2, Phosphate transporter 2, PiT-2, Pit2, hPit2, Solute carrier family 20 member 2, SLC20A2, GLVR2, PIT2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC20A2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SLC20A2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC20A2 |
|---|---|
| Synonyms | GLVR2, PIT2 |
| Function | Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:12205090, PubMed:15955065, PubMed:16790504, PubMed:17494632, PubMed:22327515, PubMed:28722801, PubMed:30704756). Plays a critical role in the determination of bone quality and strength by providing phosphate for bone mineralization (By similarity). Required to maintain normal cerebrospinal fluid phosphate levels (By similarity). Mediates phosphate-induced calcification of vascular smooth muscle cells (VCMCs) and can functionally compensate for loss of SLC20A1 in VCMCs (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Apical cell membrane {ECO:0000250|UniProtKB:Q63488}; Multi-pass membrane protein |
| Tissue Location | Ubiquitously expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Bottger,P. (2005) FEBS J. 272 (12), 3060-3074Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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