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Dkk4 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8VEJ3 |
| Other Accession | NM_145592, NP_663567 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24kDa |
| Gene ID | 234130 |
|---|---|
| Alias Symbol | Dkk-4, MGC25705 |
| Other Names | Dickkopf-related protein 4, Dickkopf-4, Dkk-4, Dkk4 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Dkk4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Dkk4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Dkk4 |
|---|---|
| Function | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). |
| Cellular Location | Secreted. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12014
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