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Atf7ip Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Atf7ip Antibody - middle region AI12052

    Host: Rabbit
    Target Name: Atf7ip
    Sample Tissue: Mouse Lung lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7TT18
Other Accession NM_019426, NP_062299
Reactivity Mouse, Rat, Pig
Predicted Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 138kDa
Additional Information
Gene ID 54343
Alias Symbol 2610204M12Rik, AM, Mcaf1
Other Names Activating transcription factor 7-interacting protein 1, ATFa-associated modulator, mAM, MBD1-containing chromatin-associated factor 1, Atf7ip, Mcaf1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Atf7ip antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAtf7ip Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Atf7ip
Synonyms Mcaf1
Function Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). May have ATPase activity.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed at all stages studied.
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$ 293.00
Cat# AI12052
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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