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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Ciao1 Antibody - N-terminal region
Ciao1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q99KN2 |
| Other Accession | NM_025296, NP_079572 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38kDa |
| Gene ID | 26371 |
|---|---|
| Alias Symbol | AW210570, Wdr39 |
| Other Names | Probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255|HAMAP-Rule:MF_03037}, WD repeat-containing protein 39 {ECO:0000255|HAMAP-Rule:MF_03037}, Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037}, Wdr39 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Ciao1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Ciao1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Ciao1 {ECO:0000255|HAMAP-Rule:MF_03037} |
|---|---|
| Synonyms | Wdr39 |
| Function | Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (By similarity). Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle- associated MMXD complex it may play a role in chromosome segregation (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O76071}. |
Research Areas
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$ 389.00
Cat# AI12072
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