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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   PLUNC antibody - middle region   

PLUNC antibody - middle region

Rabbit Polyclonal Antibody

     
  • IHC - PLUNC antibody - middle region AI12105
    Immunohistochemistry with Human Lung, respiratory epethelium tissue at an antibody concentration of 5.0μg/ml using anti-PLUNC antibody
  • WB - PLUNC antibody - middle region AI12105

    WB Suggested Anti-PLUNC Antibody Titration: 0.2-1 μg/ml
    Positive Control: Jurkat cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q9NP55
Other Accession NM_016583, NP_057667
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Bovine, Guinea Pig, Dog
Predicted Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 51297
Alias Symbol LUNX, NASG, SPLUNC1, SPURT, bA49G10.5, PLUNC, LPLUNC3
Other Names BPI fold-containing family A member 1, Lung-specific protein X, Nasopharyngeal carcinoma-related protein, Palate lung and nasal epithelium clone protein, Secretory protein in upper respiratory tracts, Short PLUNC1, SPLUNC1, Tracheal epithelium-enriched protein, Von Ebner protein Hl, BPIFA1, LUNX, NASG, PLUNC, SPLUNC1, SPURT
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PLUNC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPLUNC antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BPIFA1
Synonyms LUNX, NASG, PLUNC, SPLUNC1, SPURT
Function Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.
Cellular Location Secreted. Note=Apical side of airway epithelial cells. Detected in airway surface liquid, nasal mucus and sputum
Tissue Location Lung, upper airways and nasopharyngeal regions, including trachea and nasal epithelium. Specifically expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. Highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways. Also expressed in lung cancers and some other types of cancer.
Research Areas
Citations (0)

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References

Zhou,H.D.,(2006)Mol.Immunol.43(11),1864-1871ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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$ 293.00
Cat# AI12105
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