SLC38A4 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q969I6 |
Other Accession | NM_003345, NP_060488 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Rabbit, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 17kDa |
Gene ID | 55089 |
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Alias Symbol | ATA3, FLJ10191, MGC126876, NAT3, PAAT |
Other Names | Sodium-coupled neutral amino acid transporter 4, Amino acid transporter A3, Na(+)-coupled neutral amino acid transporter 4, Solute carrier family 38 member 4, System A amino acid transporter 3, System N amino acid transporter 3, SLC38A4, ATA3, NAT3, SNAT4 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-SLC38A4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SLC38A4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC38A4 (HGNC:14679) |
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Function | Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:11342143, PubMed:19015196, PubMed:33928121). The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+) (PubMed:11414754). Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L- proline and L-glutamine and L-methionine (PubMed:11414754, PubMed:33928121). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein Note=Microvillus membrane localization in placenta |
Tissue Location | Expressed almost exclusively in embryonic and adult liver, and at lower levels in the kidney (PubMed:11342143, PubMed:11414754). Expressed at lower levels in adult muscle and pancreas (PubMed:11414754). Detected in fetal blood vessels (PubMed:16148032). Expressed in syncytiotrophoblas of placenta during first trimester and at term (PubMed:19015196, PubMed:16148032). Highly expressed in first trimester placenta compared to term placenta (PubMed:19015196). |
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Provided below are standard protocols that you may find useful for product applications.
References
Zhu,S.,(2006)Exp.CellRes.312(7),1042-1049ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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