|Other Accession||NM_031696, NP_113884|
|Reactivity||Human, Mouse, Rat, Rabbit, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine|
|Other Names||Probable G-protein coupled receptor 88, Striatum-specific G-protein coupled receptor, Gpr88, Strg|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Gpr88 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Gpr88 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=During cortical lamination, subcellular location shifts, on the day of birth, from expression at the plasma membrane and in the cytoplasm to the nuclei of neurons. This intranuclear localization remains throughout adulthood.|
|Tissue Location||Expressed predominantly in the striatum (PubMed:11056049). Expressed also in olfactory tubercle, nucleus accumbens, amygdala, and neocortex. Spinal cord, pons, and medulla expression remains discrete (PubMed:26918661). Also expressed in peripheral tissues, including adrenal cortex (E16-E21) and cochlear ganglia (E19-postnatal day 3(P3)) and also at moderate levels in retina (E18-E19) and spleen (E21-P7) (PubMed:26918661)|
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