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ZDHHC18 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - ZDHHC18 antibody - middle region AI12138

    WB Suggested Anti-ZDHHC18 Antibody Titration: 0.2-1 μg/ml
    Positive Control: OVCAR-3 cell lysate
    ZDHHC18 is supported by BioGPS gene expression data to be expressed in OVCAR3
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NUE0
Other Accession NM_032283, NP_115659
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Additional Information
Gene ID 84243
Alias Symbol DKFZp667O2416, DHHC18, DHHC-18
Other Names Palmitoyltransferase ZDHHC18, 2.3.1.225, Zinc finger DHHC domain-containing protein 18, DHHC-18, ZDHHC18
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ZDHHC18 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsZDHHC18 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZDHHC18 {ECO:0000303|PubMed:35438208, ECO:0000312|HGNC:HGNC:20712}
Function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK (PubMed:23034182, PubMed:27481942, PubMed:35438208). Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS (PubMed:35438208). May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling (PubMed:27481942).
Cellular Location Golgi apparatus membrane; Multi-pass membrane protein
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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References

0ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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$ 389.00
Cat# AI12138
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