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ZGPAT antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8N5A5 |
| Other Accession | NM_032527, NP_115916 |
| Reactivity | Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57kDa |
| Gene ID | 84619 |
|---|---|
| Alias Symbol | GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP, RP4-583P15.3 |
| Other Names | Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6, Zinc finger CCCH domain-containing protein 9, Zinc finger and G patch domain-containing protein, ZGPAT, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-ZGPAT antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | ZGPAT antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZGPAT |
|---|---|
| Synonyms | GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC |
| Function | Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
| Cellular Location | Nucleus. |
| Tissue Location | Widely expressed.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Olsen,J.V.,(2006)Cell127(3),635-648ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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