EPB41 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P11171 |
Other Accession | NM_203343, NP_976218 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Rabbit, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 86kDa |
Gene ID | 2035 |
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Alias Symbol | 4.1R, EL1, HE |
Other Names | Protein 4.1, P4.1, 4.1R, Band 4.1, EPB4.1, EPB41, E41P |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-EPB41 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | EPB41 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EPB41 (HGNC:3377) |
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Synonyms | E41P |
Function | Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127). |
Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
References
Krauss,S.W.,(2008)Mol.Cell.Biol.28(7),2283-2294ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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