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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CLEC4M antibody - middle region   

CLEC4M antibody - middle region

Rabbit Polyclonal Antibody

  • WB - CLEC4M antibody - middle region AI12147

    WB Suggested Anti-CLEC4M Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: MCF7 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2X3
Other Accession NM_001144906, NP_001138378
Reactivity Human, Pig, Horse
Predicted Human, Pig, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Additional Information
Gene ID 10332
Alias Symbol CD299, LSIGN, CD209L, L-SIGN, DCSIGNR, HP10347, DC-SIGN2, DC-SIGNR, MGC47866, MGC129964, CLEC4M
Other Names C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, DC-SIGNR, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, CD299, CLEC4M, CD209L, CD209L1, CD299
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CLEC4M antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCLEC4M antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD209L, CD209L1, CD299
Function Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.
Cellular Location Isoform 1: Cell membrane; Single-pass type II membrane protein Isoform 3: Cell membrane; Single-pass type II membrane protein Isoform 6: Secreted. Isoform 10: Secreted.
Tissue Location Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.
Research Areas
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$ 293.00
Cat# AI12147
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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