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MPDZ antibody - middle region

Rabbit Polyclonal Antibody

     
  • IHC - MPDZ antibody - middle region AI12182
    Kidney
    detail
  • WB - MPDZ antibody - middle region AI12182

    WB Suggested Anti-MPDZ Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Human Liver
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession O75970
Other Accession NM_003829, NP_003820
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 218kDa
Additional Information
Gene ID 8777
Alias Symbol DKFZp781P216, FLJ25909, FLJ34626, FLJ90240, MUPP1
Other Names Multiple PDZ domain protein, Multi-PDZ domain protein 1, MPDZ, MUPP1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MPDZ antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMPDZ antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPDZ
Synonyms MUPP1
Function Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses (PubMed:11150294, PubMed:15312654). Promotes clustering of HT2RC at the cell surface (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic density. Cell projection, dendrite. Cell junction, tight junction. Synapse. Synapse, synaptosome Note=Colocalizes with HTR2C on the apical membrane of epithelial choroid plexus cells (By similarity). Highly enriched in postsynaptic densities (PSD). Localized to punctae on dendrites of hippocampal neurons and colocalizes with the synaptic marker DLG4. Localized mainly in the Schmidt-Lanterman incisures of myelinating Schwann cells (By similarity). In the retina, localizes to the sub-apical region adjacent to the adherens junction complex at the outer limiting membrane Enriched at the tight junctions of epithelial cells. Association to the tight junctions depends on CXADR. {ECO:0000250, ECO:0000250|UniProtKB:O55164}
Tissue Location Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
Research Areas
Citations (0)
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$ 389.00
Cat# AI12182
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