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Pard6b Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - Pard6b Antibody - N-terminal region AI12186
    Rabbit Anti-Pard6b Antibody
    Formalin Fixed Paraffin Embedded Tissue: Human Adult liver Observed Staining: Cytoplasmic,Membrane
    Primary Antibody
    Concentration: 1:600
    Secondary Antibody: Donkey anti-Rabbit-Cy2/3
    Secondary Antibody
    Concentration: 1:200
    Magnification: 20X
    Exposure Time: 0.5 – 2.0 sec
    Protocol located in Reviews and Data.
    detail
  • WB - Pard6b Antibody - N-terminal region AI12186

    Host: Rabbit
    Target Name: Pard6b
    Sample Tissue: Mouse Heart lysates
    Antibody Dilution: 1.0μg/ml
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9JK83
Other Accession NM_021409, NP_067384
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 58220
Alias Symbol AV025615, Par6b
Other Names Partitioning defective 6 homolog beta, PAR-6 beta, PAR-6B, Pard6b, Par6b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-Pard6b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPard6b Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pard6b
Synonyms Par6b
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Cellular Location Cytoplasm. Cell membrane. Cell junction, tight junction. Note=Colocalizes with active form of CDC42 or RAC1 at membrane ruffles. Also localizes to tight junctions
Tissue Location Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues
Research Areas
Citations (0)
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$ 389.00
Cat# AI12186
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