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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   INADL antibody - N-terminal region   

INADL antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - INADL antibody - N-terminal region AI12187

    WB Suggested Anti-INADL Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:12500
    Positive Control: 293T cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8NI35
Other Accession NM_176877, NP_795352
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 196kDa
Additional Information
Gene ID 10207
Alias Symbol Cipp, FLJ26982, PATJ, hINADL, InaD-like
Other Names InaD-like protein, Inadl protein, hINADL, Pals1-associated tight junction protein, Protein associated to tight junctions, INADL, PATJ
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-INADL antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsINADL antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PATJ {ECO:0000303|PubMed:22006950, ECO:0000312|HGNC:HGNC:28881}
Function Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries (PubMed:22006950).
Cellular Location Cell junction, tight junction. Apical cell membrane {ECO:0000250|UniProtKB:Q63ZW7}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q63ZW7}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q63ZW7}. Cell membrane {ECO:0000250|UniProtKB:Q63ZW7}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q63ZW7}. Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane- associated. Localizes to tight junctions in epithelial cells (PubMed:22006950). Also found at the apical plasma membrane {ECO:0000250|UniProtKB:Q63ZW7, ECO:0000269|PubMed:22006950}
Tissue Location Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain.
Research Areas
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$ 293.00
Cat# AI12187
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