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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > UBE2L3 antibody - C-terminal region
UBE2L3 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P68036 |
| Other Accession | NM_004739, NP_003338 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75kDa |
| Gene ID | 7332 |
|---|---|
| Alias Symbol | E2-F1, L-UBC, UBCH7, UbcM4 |
| Other Names | Ubiquitin-conjugating enzyme E2 L3, 6.3.2.19, L-UBC, UbcH7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3, UBE2L3, UBCE7, UBCH7 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-UBE2L3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | UBE2L3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBE2L3 |
|---|---|
| Synonyms | UBCE7, UBCH7 |
| Function | Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN, RNF31 and ARIH1, that function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis. |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Ubiquitous, with highest expression in testis. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 339.00
Cat# AI12207
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