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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RBBP6 antibody - N-terminal region   

RBBP6 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - RBBP6 antibody - N-terminal region AI12215

    WB Suggested Anti-RBBP6 Antibody Titration: 0.2-1 μg/ml
    Positive Control: NCI-H226 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z6E9
Other Accession NM_006910, NP_008841
Reactivity Human, Mouse, Rat, Rabbit, Pig, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 201kDa
Additional Information
Gene ID 5930
Alias Symbol DKFZp686P0638, DKFZp761B2423, MY038, P2P-R, RBQ-1, PACT, SNAMA
Other Names E3 ubiquitin-protein ligase RBBP6, 6.3.2.-, Proliferation potential-related protein, Protein P2P-R, Retinoblastoma-binding Q protein 1, RBQ-1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis, RBBP6, P2PR, PACT, RBQ1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RBBP6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRBBP6 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBBP6
Synonyms P2PR, PACT, RBQ1
Function E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
Cellular Location Nucleus, nucleolus. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Colocalizes with mitotic chromosomes. Colocalizes with NEK6 in the centrosome
Tissue Location Highly expressed in the placenta and testis. Expressed at lower levels in the brain, heart, kidney, liver and lung. Overexpressed in esophageal cancer
Research Areas
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$ 293.00
Cat# AI12215
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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