|Other Accession||NM_012173, NP_036305|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rabbit, Zebrafish, Chicken, Horse, Guinea Pig, Dog|
|Alias Symbol||FBX25, MGC20256, MGC51975|
|Other Names||F-box only protein 25, FBXO25, FBX25|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FBXO25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FBXO25 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity).|
|Cellular Location||Nucleus. Note=In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1|
|Tissue Location||Expressed in all brain tissue observed.|
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