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DCST1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q5T197 |
| Other Accession | NM_152494, NP_689707 |
| Reactivity | Human, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 78kDa |
| Gene ID | 149095 |
|---|---|
| Alias Symbol | FLJ32785, RP11-307C12.10 |
| Other Names | DC-STAMP domain-containing protein 1, DCST1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DCST1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | DCST1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DCST1 |
|---|---|
| Function | E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteasomal degradation thereby negatively regulating type-I-interferon signaling. Essential sperm cell-surface protein required for sperm-egg fusion and fertilization (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:Q059Y8}; Multi-pass membrane protein. Note=Localizes in the anterior acrosome before the acrosome reaction and then translocates to the equatorial segment in acrosome-reacted sperm {ECO:0000250|UniProtKB:Q059Y8} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12275
Ordering Information
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