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ABCG5 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - ABCG5 antibody - middle region AI12315

    WB Suggested Anti-ABCG5 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Human Spleen
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9H222
Other Accession NM_022436, NP_071881
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Additional Information
Gene ID 64240
Alias Symbol STSL
Other Names ATP-binding cassette sub-family G member 5, Sterolin-1, ABCG5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ABCG5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsABCG5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCG5 (HGNC:13886)
Function ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11138003, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11138003, PubMed:15054092). The heterodimer with ABCG8 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Cellular Location Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein
Tissue Location Strongly expressed in the liver, lower levels in the small intestine and colon.
Research Areas
Citations (0)
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$ 389.00
Cat# AI12315
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