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SLC4A2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P04920 |
| Other Accession | NM_003040, NP_003031 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 137kDa |
| Gene ID | 6522 |
|---|---|
| Alias Symbol | AE2, BND3L, EPB3L1, HKB3, NBND3 |
| Other Names | Anion exchange protein 2, AE 2, Anion exchanger 2, Non-erythroid band 3-like protein, BND3L, Solute carrier family 4 member 2, SLC4A2, AE2, EPB3L1, HKB3, MPB3L |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC4A2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SLC4A2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC4A2 |
|---|---|
| Synonyms | AE2, EPB3L1, HKB3, MPB3L |
| Function | Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:15184086, PubMed:34668226). Plays an important role in osteoclast differentiation and function (PubMed:34668226). Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity). Essential for intracellular pH regulation in CD8(+) T- cells upon CD3 stimulation, modulating CD8(+) T-cell responses (By similarity). |
| Cellular Location | [Isoform A]: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein [Isoform B2]: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein |
| Tissue Location | [Isoform A]: Expressed in the liver, stomach, kidney, prostate, thyroid and rectum. [Isoform B2]: Expressed in the liver and kidney. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12330
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