Epor antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P14753 |
Other Accession | NM_010149, NP_034279 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 55kDa |
Gene ID | 13857 |
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Other Names | Erythropoietin receptor, EPO-R, Epor |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Epor antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Epor antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Epor |
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Function | Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. |
Cellular Location | [Isoform EPOR-F]: Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells |
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