|Application ||WB, IHC|
|Other Accession||NM_000348, NP_000339|
|Reactivity||Human, Rabbit, Pig|
|Predicted||Human, Rabbit, Pig|
|Other Names||3-oxo-5-alpha-steroid 4-dehydrogenase 2, 220.127.116.11, 5 alpha-SR2, SR type 2, Steroid 5-alpha-reductase 2, S5AR 2, SRD5A2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SRD5A2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SRD5A2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.|
|Cellular Location||Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein|
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