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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   CISD2 antibody - N-terminal region   

CISD2 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - CISD2 antibody - N-terminal region AI12443

    WB Suggested Anti-CISD2 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Transfected 293T
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N5K1
Other Accession NM_001008388, NP_001008389
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 15kDa
Additional Information
Gene ID 493856
Alias Symbol ERIS, Miner1, WFS2, ZCD2, NAF-1
Other Names CDGSH iron-sulfur domain-containing protein 2, Endoplasmic reticulum intermembrane small protein, MitoNEET-related 1 protein, Miner1, Nutrient-deprivation autophagy factor-1, NAF-1, CISD2, CDGSH2, ERIS, ZCD2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CISD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCISD2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CISD2
Synonyms CDGSH2, ERIS, ZCD2
Function Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane
Tissue Location Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets.
Research Areas
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$ 293.00
Cat# AI12443
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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