LRRC26 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q2I0M4 |
Other Accession | NM_001013653, NP_001013675 |
Reactivity | Human, Horse, Bovine, Guinea Pig, Dog |
Predicted | Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37kDa |
Gene ID | 389816 |
---|---|
Alias Symbol | bA350O14.10, CAPC |
Other Names | Leucine-rich repeat-containing protein 26, BK channel auxiliary gamma subunit LRRC26, Cytokeratin-associated protein in cancer, LRRC26, CAPC |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LRRC26 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | LRRC26 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LRRC26 |
---|---|
Synonyms | CAPC |
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels. |
Tissue Location | Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines |
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Provided below are standard protocols that you may find useful for product applications.
References
Egland,K.A.,(2006)Proc.Natl.Acad.Sci.U.S.A.103(15),5929-5934ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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