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LRRC26 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - LRRC26 antibody - middle region AI12474

    WB Suggested Anti-LRRC26 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Jurkat cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q2I0M4
Other Accession NM_001013653, NP_001013675
Reactivity Human, Horse, Bovine, Guinea Pig, Dog
Predicted Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 37kDa
Additional Information
Gene ID 389816
Alias Symbol bA350O14.10, CAPC
Other Names Leucine-rich repeat-containing protein 26, BK channel auxiliary gamma subunit LRRC26, Cytokeratin-associated protein in cancer, LRRC26, CAPC
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-LRRC26 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLRRC26 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRC26
Synonyms CAPC
Function Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels.
Tissue Location Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines
Research Areas
Citations (0)
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References

Egland,K.A.,(2006)Proc.Natl.Acad.Sci.U.S.A.103(15),5929-5934ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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$ 389.00
Cat# AI12474
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