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Ano6 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Ano6 antibody - middle region AI12495

    WB Suggested Anti-Ano6 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6P9J9
Other Accession NM_175344, NP_780553
Reactivity Human, Mouse, Rat, Pig, Guinea Pig
Predicted Human, Mouse, Rat, Pig, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 106kDa
Additional Information
Gene ID 105722
Alias Symbol 2900059G15Rik, AA407480, AW554778, F730003B03Rik, Tmem16f
Other Names Anoctamin-6, Small-conductance calcium-activated nonselective cation channel, SCAN channel, Transmembrane protein 16F, Ano6, Tmem16f
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Ano6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAno6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ano6
Synonyms Tmem16f
Function Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets, osteoblasts and fetal thymocytes. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q4KMQ2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q4KMQ2}. Note=Shows an intracellular localization. {ECO:0000250|UniProtKB:Q4KMQ2}
Tissue Location Predominant expression seen in epithelial tissues. Also found in skeletal system where it is primarily expressed in osteoblasts.
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$ 293.00
Cat# AI12495
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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