|Other Accession||NM_002569, NP_002560|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Sheep, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Sheep, Horse, Bovine, Dog|
|Alias Symbol||FUR, PACE, PCSK3, SPC1|
|Other Names||Furin, 184.108.40.206, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE, FURIN, FUR, PACE, PCSK3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FURIN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FURIN antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FUR, PACE, PCSK3|
|Function||Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin|
|Tissue Location||Seems to be expressed ubiquitously.|
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