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FURIN antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - FURIN antibody - N-terminal region AI12564

    WB Suggested Anti-FURIN Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09958
Other Accession NM_002569, NP_002560
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Sheep, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 74kDa
Additional Information
Gene ID 5045
Alias Symbol FUR, PACE, PCSK3, SPC1
Other Names Furin,, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE, FURIN, FUR, PACE, PCSK3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-FURIN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFURIN antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FUR, PACE, PCSK3
Function Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin
Tissue Location Seems to be expressed ubiquitously.
Research Areas
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$ 293.00
Cat# AI12564
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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