|Other Accession||NM_032949, NP_116567|
|Reactivity||Human, Rabbit, Horse, Guinea Pig, Dog|
|Predicted||Human, Rabbit, Horse, Guinea Pig, Dog|
|Alias Symbol||ARCADLIN, PAPC|
|Other Names||Protocadherin-8, Arcadlin, PCDH8|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PCDH8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PCDH8 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Cell junction, synapse, presynaptic cell membrane Cell junction, synapse, postsynaptic cell membrane. Note=Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses.|
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