PCDH8 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O95206 |
Other Accession | NM_032949, NP_116567 |
Reactivity | Human, Rabbit, Horse, Guinea Pig, Dog |
Predicted | Human, Rabbit, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 101kDa |
Gene ID | 5100 |
---|---|
Alias Symbol | ARCADLIN, PAPC |
Other Names | Protocadherin-8, Arcadlin, PCDH8 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PCDH8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PCDH8 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PCDH8 |
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Function | Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Presynaptic cell membrane. Postsynaptic cell membrane Note=Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses. |
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Provided below are standard protocols that you may find useful for product applications.
References
Lim,J.,(2006)Cell125(4),801-814ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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