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Mfng antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Mfng antibody - middle region AI12573

    WB Suggested Anti-Mfng Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Thymus
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O09008
Other Accession NM_008595, NP_032621
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Additional Information
Gene ID 17305
Alias Symbol AW546563
Other Names Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, 2.4.1.222, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, Mfng
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Mfng antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMfng antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mfng {ECO:0000312|MGI:MGI:1095404}
Function Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (PubMed:10935626, PubMed:28089369).
Cellular Location Golgi apparatus membrane; Single- pass type II membrane protein
Research Areas
Citations (0)
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$ 389.00
Cat# AI12573
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