|Application ||WB, IHC|
|Other Accession||NM_003748, NP_003739|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Horse|
|Alias Symbol||ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS|
|Other Names||Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, P5C dehydrogenase, 22.214.171.124, Aldehyde dehydrogenase family 4 member A1, L-glutamate gamma-semialdehyde dehydrogenase, ALDH4A1, ALDH4, P5CDH|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-ALDH4A1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ALDH4A1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.|
|Cellular Location||Mitochondrion matrix.|
|Tissue Location||Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas|
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