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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   SBDS antibody - C-terminal region   

SBDS antibody - C-terminal region

Rabbit Polyclonal Antibody

  • IHC - SBDS antibody - C-terminal region AI12612
    Human kidney
  • WB - SBDS antibody - C-terminal region AI12612

    WB Suggested Anti-SBDS Antibody Titration: 1.25μg/ml
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y3A5
Other Accession NM_016038, NP_057122
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 51119
Alias Symbol CGI-97, FLJ10917, SDS, SWDS
Other Names Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein, SBDS
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-SBDS antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSBDS antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP- dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
Cellular Location Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 and PubMed:17475909). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (PubMed:19759903).
Tissue Location Widely expressed.
Research Areas
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$ 232.00
Cat# AI12612
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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