|Application ||WB, IHC, IP|
|Other Accession||NM_016312, NP_057396|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Guinea Pig, Dog|
|Alias Symbol||DKFZp779M1063, NPWBP, SIPP1, WBP-11|
|Other Names||WW domain-binding protein 11, WBP-11, Npw38-binding protein, NpwBP, SH3 domain-binding protein SNP70, Splicing factor that interacts with PQBP-1 and PP1, WBP11, NPWBP, SIPP1, SNP70|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-WBP11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||WBP11 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NPWBP, SIPP1, SNP70|
|Function||Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.|
|Cellular Location||Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin|
|Tissue Location||Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung|
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