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Dag1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q62165 |
| Other Accession | NM_010017, NP_034147 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 97kDa |
| Gene ID | 13138 |
|---|---|
| Alias Symbol | D9Wsu13e, DG, Dp427, Dp71 |
| Other Names | Dystroglycan, Dystrophin-associated glycoprotein 1, Alpha-dystroglycan, Alpha-DG, Beta-dystroglycan, Beta-DG, Dag1, Dag-1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Dag1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Dag1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Dag1 {ECO:0000312|MGI:MGI:101864} |
|---|---|
| Function | The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. [Beta-dystroglycan]: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity (By similarity). |
| Cellular Location | [Alpha-dystroglycan]: Secreted, extracellular space |
| Tissue Location | Detected in brain and kidney (at protein level) (PubMed:16709410). Detected in sciatic nerve (at protein level) (PubMed:11430802). Expressed in neurons and muscle cells (at protein level) (PubMed:25757569). Expressed in a variety of tissues. In brain, expressed in the hippocampal formation, the olfactory bulb, the cerebellum and the thalamus. In the peripheral nerve system, expressed in Schwann cells. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12681
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