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> home > Products > Primary Antibodies > Signal Transduction > HS3ST3B1 antibody - N-terminal region
HS3ST3B1 antibody - N-terminal region
Rabbit Polyclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q9Y662 |
| Other Accession | NM_006041, NP_006032 |
| Reactivity | Human, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 43kDa |
| Gene ID | 9953 |
|---|---|
| Alias Symbol | 30ST3B1, 3OST3B1 |
| Other Names | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1, 2.8.2.30, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, 3-OST-3B, Heparan sulfate 3-O-sulfotransferase 3B1, h3-OST-3B, HS3ST3B1, 3OST3B1, HS3ST3B |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HS3ST3B1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | HS3ST3B1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HS3ST3B1 |
|---|---|
| Synonyms | 3OST3B1, HS3ST3B |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate (PubMed:10520990, PubMed:9988768). Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 (PubMed:10520990, PubMed:9988768). The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry (PubMed:10520990). Unlike HS3ST1/3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (PubMed:9988768). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Moon,A.F.,(2004)J.Biol.Chem.279(43),45185-45193ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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$ 389.00
Cat# AI12703
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