|Other Accession||NM_006041, NP_006032|
|Reactivity||Human, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Pig, Horse, Bovine, Dog|
|Alias Symbol||30ST3B1, 3OST3B1|
|Other Names||Heparan sulfate glucosamine 3-O-sulfotransferase 3B1, 22.214.171.124, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, 3-OST-3B, Heparan sulfate 3-O-sulfotransferase 3B1, h3-OST-3B, HS3ST3B1, 3OST3B1, HS3ST3B|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-HS3ST3B1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||HS3ST3B1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney|
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