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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Tmed1 antibody - N-terminal region
Tmed1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q5BK85 |
| Other Accession | NM_001013432, NP_001013450 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25kDa |
| Gene ID | 315461 |
|---|---|
| Alias Symbol | Il1rl1l, MGC108769, Tmed1 |
| Other Names | Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, p24 family protein gamma-1, p24gamma1, Tmed1, Il1rl1l |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Tmed1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Tmed1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Tmed1 |
|---|---|
| Synonyms | Il1rl1l |
| Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Plays also a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q13445}; Single-pass type I membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q13445}; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q13445}; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q13445}; Single-pass type I membrane protein |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12712
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