|Other Accession||NM_007052, NP_008983|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Zebrafish, Pig, Chicken, Horse, Bovine, Dog|
|Alias Symbol||GP91-2, MOX1, NOH-1, NOH1|
|Other Names||NADPH oxidase 1, NOX-1, 1.-.-.-, Mitogenic oxidase 1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1, NOX1, MOX1, NOH1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-NOX1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NOX1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.|
|Cellular Location||Cell projection, invadopodium membrane; Multi-pass membrane protein|
|Tissue Location||NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH- 1S is detected only in colon and colon carcinoma cells|
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